Abstract
Forensic histopathology is the application of histological techniques and examination to forensic pathology practice.1 Histopathology is usually done at autopsy to ascertain the cause of death, if macroscopic features are obscure, unreliable or unremarkable. Poisoning is a major cause of mortality and morbidity in India contributing a significant portion to the annual deaths and DALYs’. Deaths due to poisoning can sometimes be challenging and often attributable to the absence of significant macroscopic findings at autopsy. Frequently the toxicological analysis reports also, may not reveal the type of poison causing a serious challenge in formulating the cause and manner of death. We have presented two cases of deaths due to paracetamol and iron overdose and highlighted the importance of histopathology in identifying the type of poison. The cases mentioned in this article are those of medication poisoning
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Download PDF- Lau G, Lai SH. Forensic Pathology Reviews. 1st ed. New Jersey: Humana Press; 2009.239-265p.
- Wennig R. Encyclopedia of Forensic Sciences. 3rd ed. Amsterdam: Elsevier; 2013. 205-209 p.
- India: mortality rate due to unintentionalpoisoning [Internet][cited 2022 Oct 12]. Available from: https:/ /www.statista.com/statistics/1132542/india-mortality rate-due-to-unintentional-poisoning/.
- Mohanty MK, Pinnamaneni S, Arun M, Menezes RG, Palimar V. Correlation between post-mortem diagnosis and survival time in poisoning deaths. Journal of Indian Academy of Forensic Medicine. 2005; 27(1):23-7.
- Battal D, Hilal A, Daglioglu K, Unal I, Gulmen M. Evaluation of paracetamol distribution and stability in case of acute intoxication in rats. Hum Exp Toxicol. 2013 Jan;32(1):82–9.
- Dettmeyer RB, Verhoff MA, Schütz HF. Forensic medicine: fundamentals and perspectives. Springer Science & Business Media; 2013 Oct 9.
- Cummings PM, Trelka DP, Springer KM. Atlas of forensic histopathology. Cambridge: Cambridge university press; 2011.
- Iron Poisoning: Symptoms and Treatments [Internet]. Healthline. 2017 [cited 2022 Oct 12]. Available from: https://www.healthline.com/health/iron-poisoning
- Yu D, Giffen MA. Suicidal iron overdose: A case report and review of literature. J Forensic Sci. 2021 Jul;66(4):1564–9.
- Yuen HW, Becker W. Iron Toxicity. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 2022 Oct 12]. Available from: http:// www.ncbi.nlm.nih.gov/books/NBK459224
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