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Home▶ Journals▶ Indian Journal of Veterinary Sciences and Biotechnology▶Archive▶Vol. 7 No. 4 (2012)▶Anti Ulcer Activity Of Curcuma Longa Against Indomethacin…
Indian Journal of Veterinary Sciences and Biotechnology
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Anti Ulcer Activity Of Curcuma Longa Against Indomethacin Induced Gastric Ulcers In Albino Rats

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R. Nagle — Department of Pharmacology and Toxicology College of Veterinary Science and Animal Husbandry, Jabalpur (M.P.) MPPCVV, Jabalpur, M.P. 482001, India
K. Shrman — Department of Pharmacology and Toxicology College of Veterinary Science and Animal Husbandry, Jabalpur (M.P.) MPPCVV, Jabalpur, M.P. 482001, India
R. K. Sharma — Department of Pharmacology and Toxicology College of Veterinary Science and Animal Husbandry, Jabalpur (M.P.) MPPCVV, Jabalpur, M.P. 482001, India
Published 20 Feb 2012 Vol. 7 No. 4 (2012), pp. 29-31 ● Open access
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Abstract

In the present study, anti ulcer activity of Curcuma longa was evaluated against Indomethacine induced gastric ulcers in rats. The ulcers were produced by oral administration of indomethacin @ 15 mg/kg b.w. The extract of C. longa was given @ 600 mg/kg b.w. by oral route to the experimental albino rats. Ranitidine was used as standard drug. Alcoholic extract of C. longa significantly reduce the number and severity of the gastric ulcers by lowering ulcer index and ulcer score and increasing healing index indicating the ulcer protective action of C.longa. 

KeywordsCurcuma longaindomethacingastric ulcerulcer scorehealing index

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