Skip to content
Home▶ Journals▶ Indian Journal of Veterinary Sciences and Biotechnology▶Archive▶Vol. 13 No. 4 (2018)▶Safety Evaluation of repeated oral administration of…
Indian Journal of Veterinary Sciences and Biotechnology
Articles

Safety Evaluation of repeated oral administration of Gemifloxacin in Broiler Birds

, , ,
R.H. Gohel — Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand-388001, Gujarat, India
K.A. Sadariya — Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand-388001, Gujarat, India
J. J. Maradiya — Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand-388001, Gujarat, India
A.M. Thaker — Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand-388001, Gujarat, India
Published 8 Apr 2018 Vol. 13 No. 4 (2018), pp. 1-4 ● Open access
Download PDF

Abstract

Gemifloxacin is a fourth generation fluoroquinolone drug having broad-spectrum and good antibacterial activity at low plasma/tissue concentration. The present study was designed to investigate safety of gemifloxacin @ 10 mg/kg body weight after repeated oral administration at 24 hr interval for 5 days in 6 broiler birds of 5-6 week age. It was found safe based on non-significant alteration in haematological (Hb, PCV, TEC and TLC) and serum biochemical (AST, ALT, ACP, ALP, LDH, creatinine, total bilirubin and uric acid) parameters that were evaluated before and at 24 hourly interval for 5 days during treatment. 

KeywordsGemifloxacinBroiler birdsHaematologySerum Biochemistry

The full text of this article is available as a PDF.

Download PDF

Looking up citing articles…