Immunomodulatory effect of Neem (Azadiracta indica) Extract on Recovery and Conception Rate in Infectious Repeat Breeder Crossbred Cows

The study was undertaken to evaluate the therapeutic efficacy of Neem (Azadiracta indica) extract in 20 infectious repeat breeder crossbred cows. Animals were divided into two groups of ten in each. The animals in first group were treated with 15% concentration of Neem extract w/v dissolved in saline to make 30 ml, Intra Uterine at 24 hrs intervals for 7 days, while the animals in control group were infused with 30 ml saline for 7 days. Bacterial count in uterine flushing declined significantly (p<0.05) after treatment in Neem group. A significant increase (p<0.05) in total cellular count and PMNs % was found in Neem group than in control group. An overall recovery rate of 80% vs 20% and conception rate of 50% vs 10% was found in Neem treated cows over control group proving its efficacy in infectious repeat breeder cows.