Abstract
The present study investigated on 12 clinically healthy pregnant Surti goats carrying twin foetuses which were randomly allocated into two groups (n=6 each): a control group (routine diet) and a supplemented group (diet supplemented with Tinospora cordifolia [Giloy] stem powder @ 6% of the total concentrate mixture for 30 days prepartum to 30 days postpartum). Blood samples were collected at days -30, -20, -10, -5 before kidding, on the day of kidding (0) and days +5, +10, +20, +30 after kidding to evaluate haematological parameters. Results indicated that erythrocytic parameters (TEC, Hb and PCV) followed physiological peri-parturient fluctuations with no significant differences between groups. However, Tinospora cordifolia supplementation significantly (p<0.05) improved leukocyte dynamics, evidenced by higher total leukocyte, neutrophil and lymphocyte counts and a significantly (p<0.05) lower neutrophil-to lymphocyte ratio around kidding, suggesting enhanced immune competence and reduced stress response. In conclusion, Tinospora cordifolia supplementation exerted beneficial immunomodulatory effects during the periparturient period, supporting its potential use as a natural phytogenic supplement to enhance physiological resilience in twin-bearing Surti goats.
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Download PDF- Azab, M. E., & Abdel-Maksoud, H. A. (1999). Changes in some hematological and biochemical parameters during prepartum and postpartum periods in female Baladi goats. Small Ruminant Research, 34(1), 77–85.
- Bhattacharyya, C., & Bhattacharyya, G. (2013). Therapeutic potential of Giloe, Tinospora cordifolia (Willd.) Hook. f. & Thomson (Menispermaceae): The magical herb of Ayurveda. International Journal of Pharmaceutical and Biological Archives, 4, 558–584.
- Farrag, B. (2024). Effect of the addition of Moringa oleifera leaves on reproduction, hematological, biochemical parameters, and milk yield and composition of goats under arid conditions of Siwa Oasis. Alexandria Journal of Veterinary Sciences, 82, 1–10.
- Goff, J. P. (2006). Major advances in our understanding of nutritional influences on bovine health. Journal of Dairy Science, 89(4), 1292–1301.
- Iriadam, M. (2007). Variation in certain hematological and biochemical parameters during the peri-partum period in Kilis does. Small Ruminant Research, 73(1–3), 54–57.
- Mallick, S., & Prakash, B. S. (2011). Effects of supplementation of Tinospora cordifolia to crossbred cows peripartum. Animal Reproduction Science, 123(1–2), 5–13.
- Pattanayak, S., Mandal, T. K., & Bandyopadhyay, S. K. (2016). Validation and therapeutic use of succulent plant parts opening of a new horizon of alternative medicine. Exploratory Animal and Medical Research, 6(1), 8–14.
- Samui, T., Ghosh, P. R., Das, P. K., Banerjee, D., Naskar, S., Bag, S., & Mukherjee, J. (2023). Alterations in the haemato-biochemical, endocrine and in vitro immune competence of leukocytes in Black Bengal does (Capra hircus) during periparturient period. Indian Journal of Animal Health, 62(2), 222–227.
- Snedecor, G. W., & Cochran, W. G. (2014). Statistical methods (8th ed.). The Iowa State University Press.
- Sordillo, L. M. (2016). Nutritional strategies to optimize dairy cattle immunity. Journal of Dairy Science, 99(6), 4967–4982.
- Tharwat, M., Ali, A., & Al-Sobayil, F. (2015). Hematological and biochemical profiles in goats during the transition period. Comparative Clinical Pathology, 24(1), 1–7.
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