Comprehensive Cardiac Assessment in Dogs using Electrocardiography, Echocardiography and Cardiac Biomarkers
DOI:
https://doi.org/10.48165/ijvsbt.2026.22.06.20Keywords:
Cardiac disease, Cardiac troponin-I, Dog, ECG, Echocardiography, NT-proBNPAbstract
Cardiac diseases are a major cause of morbidity and mortality in dogs and require timely diagnosis for effective clinical management. A total of 52 dogs with clinical suspicion of cardiac disease were examined and compared with six apparently healthy control dogs at Veterinary Clinical Complex, Kamdhenu University, Navsari, Gujarat. Diagnosis was established using ECG and echocardiography and supported by haemato-biochemical analysis and assessment of cardiac troponin-I (cTnI) and N-terminal pro-B-type natriuretic peptide (NT-proBNP). Dilated cardiomyopathy (DCM) was the most prevalent cardiac disorder (46.15%), followed by mitral valve disease (MVD) (38.46%), pericardial effusion (11.53%), and hypertrophic cardiomyopathy (3.84%). The most common clinical signs were exercise intolerance (92.30%), dyspnea (88.46%), and weakness (86.53%). ECG revealed atrial fibrillation (30.76%) and sinus tachycardia (25.00%) as the predominant rhythm abnormalities. Echocardiography demonstrated significant ventricular dilatation, increased E-point to septal separation, and reduced ejection fraction and fractional shortening in DCM, whereas MVD was characterized by marked left atrial enlargement and an increased left atrial-to-aortic root ratio. Haematological findings revealed mild anaemia, neutrophilia, and lymphopenia, while biochemical alterations were characterized by increased BUN and reduced serum albumin concentrations. Cardiac biomarkers showed marked diagnostic value, with elevated NT-proBNP concentrations and positive cTnI results in 70% of affected dogs. The findings indicate that ECG, echocardiography and cardiac biomarkers are valuable complementary tools for the accurate diagnosis and assessment of canine cardiac diseases.
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Arcuri, G., Valente, C., Perini, C., & Guglielmini, C. (2024). Risk factors for atrial fibrillation in the dog: A systematic review. Veterinary Sciences, 11(1), 47.
Bodh, D., Hoque, M., Saxena, A. C., Gugjoo, M. B., Bist, D., & Chaudhary, J. K. (2016). Vertebral scale system to measure heart size in thoracic radiographs of Indian Spitz, Labrador Retriever and Mongrel dogs. Veterinary World, 9(4), 371–376.
Boon, J. A. (2011). Veterinary echocardiography. John Wiley & Sons.
Borgarelli, M., & Haggstrom, J. (2010). Canine degenerative myxomatous mitral valve disease: Natural history, clinical presentation and therapy. Veterinary Clinics: Small Animal Practice, 40(4), 651–663.
Creevy, K. E., Akey, J. M., Kaeberlein, M., & Promislow, D. E. (2022). An open science study of ageing in companion dogs. Nature, 602(7895), 51–57.
Guglielmini, C., Valente, C., Romito, G., Mazzoldi, C., Baron Toaldo, M., Goncalves Sousa, M., & Poser, H. (2023). Risk factors for atrial fibrillation in dogs with dilated cardiomyopathy. Frontiers in Veterinary Science, 10, 1183689.
Hamilton-Elliott, J., Ambrose, E., Christley, R., & Dukes-McEwan, J. (2018). White blood cell differentials in dogs with congestive heart failure (CHF) in comparison to those in dogs without cardiac disease. Journal of Small Animal Practice, 59(6), 364–372.
Kaneko, J. J., Harvey, J. W., & Bruss, M. L. (2008). Clinical biochemistry of domestic animals (6th ed.). Academic Press.
Keene, B. W., Atkins, C. E., Bonagura, J. D., Ettinger, S. J., Fox, P. R., Gordon, S. G., Haggstrom, J., Hamlin, R. L., Keene, B. W., Luis Fuentes, V., Oyama, M. A., Rush, J. E., & Stepien, R. L. (2019). ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine, 33(3), 1127–1140.
Kittleson, M. D. (1998). Congenital pulmonic stenosis. In Small animal cardiovascular medicine (pp. 248–259). Mosby.
Luis Fuentes, V., Abbott, J., Chetboul, V., Côté, E., Fox, P. R., Häggström, J., et al. (2020). ACVIM consensus statement guidelines for the classification, diagnosis, and management of cardiomyopathies in dogs. Journal of Veterinary Internal Medicine, 34(3), 1061–1077.
Mattoon, J. S., & Nyland, T. G. (2020). Fundamentals of diagnostic ultrasound. In J. S. Mattoon & T. G. Nyland (Eds.), Small animal diagnostic ultrasound (3rd ed., pp. 1–49). Elsevier.
Moise, N. S. (2006). Advances and clinical utility of ambulatory ECG monitoring. In Proceedings of the World Small Animal Veterinary Association (WSAVA) World Congress, Prague, Czech Republic.
Na, Y., Lee, D., Yun, T., Koo, Y., Chae, Y., Kim, H., & Kang, B. T. (2021). Comparison of electrocardiographic parameters in dogs with different stages of myxomatous mitral valve disease. Canadian Journal of Veterinary Research, 85(4), 261–270.
Ogawa, M., Ogi, H., Miyakawa, H., Hori, T., Yamashita, Y., & Sasaki, N. (2022). Evaluation of the association between electrocardiogram parameters and left cardiac remodelling in dogs with myxomatous mitral valve disease. Veterinary World, 15(8), 2072–2083.
Oyama, M. A., & Singletary, G. E. (2010). The use of NT-proBNP assay in the management of canine patients with heart disease. Veterinary Clinics: Small Animal Practice, 40(4), 545–558.
Oyama, M. A., Fox, P. R., Rush, J. E., Rozanski, E. A., & Lesser, M. (2008). Clinical utility of serum N-terminal pro-B-type natriuretic peptide concentration for identifying cardiac disease in dogs and assessing disease severity. Journal of the American Veterinary Medical Association, 232(10), 1496–1503.
Oyama, M. A., Scansen, B. A., Boswood, A., Goldfeder, G., Rosenthal, S., Cober, R., & Li, Q. (2023). Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease. Journal of Veterinary Internal Medicine, 37(4), 1323–1330.
Rajkumar, K., & Kamran, C. A. (2025). Demographic studies on various cardiac diseases in dogs. International Journal of Veterinary & Animal Science Research, 45(2), 566–573.
Rubio, C. P., Saril, A., Kocaturk, M., Tanaka, R., Koch, J., Ceron, J. J., & Yilmaz, Z. (2020). Changes of inflammatory and oxidative stress biomarkers in dogs with different stages of heart failure. BMC Veterinary Research, 16(1), 433.
Schrope, D. P. (2015). Prevalence of congenital heart disease in 76,301 mixed-breed dogs and 57,025 mixed-breed cats. Journal of Veterinary Cardiology, 17(3), 192–202.
Tidholm, A., & Jonsson, L. (1997). A retrospective study of canine dilated cardiomyopathy (189 cases). Journal of the American Animal Hospital Association, 33(6), 544–550.
Tilley, L. P., & Burtnick, N. (1999). ECG for the small animal practitioner. Teton New Media.
Tilley, L. P., Smith, F. W., Sleeper, M. M., & Kraus, M. (Eds.). (2024). Manual of canine and feline cardiology (5th ed.). Elsevier Health Sciences.
Winter, R. L., Saunders, A. B., Gordon, S. G., Buch, J. S., & Miller, M. W. (2017). Biologic variability of N-terminal pro-brain natriuretic peptide in healthy dogs and dogs with myxomatous mitral valve disease. Journal of Veterinary Cardiology, 19(2), 124–131.
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