Effect of Oral Medroxyprogesterone Acetate and Nutritional Supplementation during Late Gestation on Birth Weight in Nellore Sheep
DOI:
https://doi.org/10.48165/ijvsbt.22.4.28Keywords:
Birth weight, Liquid nutritional supplement, Medroxy progesterone acetate, Nellore ewesAbstract
The present study was conducted to evaluate the effect of oral medroxy progesterone acetate and a liquid nutritional supplement on birth weight and early growth performance in Nellore ewes and their lambs under extensive rearing conditions. A total of 120 second-lambed Nellore ewes in mid to late gestation were randomly allotted into four experimental groups (n=30 each). Group I served as Control, Group II as medroxy progesterone (10 mg tab daily for 5 days), Group III liquid nutritional supplement (5 mL tonic daily for 7 days) and Group IV with combination of medroxy progesterone acetate and liquid nutritional tonic, administered orally during late gestation as above. Mean birth weights of lambs in Group II and Group III were 3.91 ± 0.41, 3.58 ± 0.31 kg against 2.96 ± 0.15 kg in the control group (p<0.01), while a combined supplement group gave the highest birth weight of 4.15 ± 0.42 kg. The findings suggested that hormonal and nutritional interventions during late pregnancy can improve lamb birth weight, which is critical for survival and postnatal growth under free-range sheep rearing systems.
Downloads
References
Ahmadzadeh-Gavahan, L., Hosseinkhani, A., Palangi, V., & Lackner, M. (2023). Supplementary feed additives can improve lamb performance in terms of birth weight, body size, and survival rate. Animals, 13, 993–1008.
Castillo-Gutierrez, D., Hernández-Arteaga, L. E. S., Flores-Najera, M. J., et al. (2022). Methionine supplementation during pregnancy of goats improves kids’ birth weight, body mass index, and postnatal growth pattern. Biology, 11, 1065–1075.
Fraga, F. J. R., Lagisz, M., Nakagawa, S., Lopez-Villalobos, N., Blair, H. T., & Kenyon, P. R. (2018). Meta-analysis of lamb birth weight as influenced by pregnancy nutrition of multiparous ewes. Journal of Animal Science, 96, 1962–1977.
Gao, F., Hou, X. Z., Liu, Y. C., Wu, S. Q., & Ao, C. J. (2008). Effect of maternal undernutrition during late pregnancy on lamb birth weight. Asian-Australasian Journal of Animal Sciences, 21(3), 371–375.
Gardner, D. S., Buttery, P. J., Daniel, Z., & Symonds, M. E. (2007). Factors affecting birth weight in sheep: Maternal environment. Reproduction, 133(1), 297–307.
Garoussi, M. T., Mavadati, O., Bahonar, M., & Ragh, M. J. (2020). The effect of medroxyprogesterone acetate with or without eCG on conception rate of fat-tail ewes in out of breeding season. Tropical Animal Health and Production, 52(4), 1617–1622.
Godfrey, K. M. (2002). The role of the placenta in fetal programming: A review. Placenta, 23(Suppl. A), 20–27.
Naveena, K., Jyosthna, M. K., Hem Kumar, B., & Madhuri, K. (2025). Effect of supplementing concentrate feed to ewes in late pregnancy and creep feed supplementation to lambs on their growth. International Journal of Veterinary Sciences and Animal Husbandry, 10(2), 34–36.
Rangamma, B., Sarat Chandra, A., Rajannan, N., Gnana Prakash, M., Venkateswarulu, M., & Hari Krishna, C. (2023). Growth performance and biometry of Nellore brown lambs from birth to weaning under different systems of rearing. Indian Journal of Animal Research, 57(4), 527–531.
Redmer, D. A., Wallace, J. M., & Reynolds, L. P. (2004). Effect of nutrient intake during pregnancy on fetal and placental growth and vascular development. Domestic Animal Endocrinology, 27, 199–217.
Rhind, S. M. (2004). Effects of maternal nutrition on fetal and neonatal reproductive development and function. Animal Reproduction Science, 82, 169–181.
Ronald, K., & Kalkhoff, M. D. (1982). Metabolic effects of progesterone. American Journal of Obstetrics and Gynecology, 142, 735–738.
Shilpa, M. W., & Ravindranath, N. K. (2018). Sheep rearing in Indian agrarian economy: Issues and facts. Journal of Emerging Technologies and Innovative Research, 5(7), 260–262.
Shivakumar, C., Reddy, B. S., & Patil, S. S. (2020). Socio-economic characteristics and composition of sheep and goat farming under extensive system of rearing. Agricultural Science Digest, 40(1), 105–108.
Spencer, T. E., & Bazer, F. W. (2002). Biology of progesterone action during pregnancy recognition and maintenance of pregnancy. Frontiers in Bioscience, 7, 18794–18798.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Indian Journal of Veterinary Sciences and Biotechnology

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

