Abstract
Transmissible venereal tumor (TVT) is one of the most common tumors in canines that mainly spread via mating. These tumors grow on the external genitalia and appear like cauliflower growth which can be nodular, papillary, pedunculated, or multilobulated and may cause serosanguinous discharge or bleeding from preputial orifices and genital canal in males and females, respectively (Panchkhande et al., 2019). It is also referred as venereal granuloma, canine transmissible venereal sarcoma, transmissible lymphosarcoma, and sticker tumor of mesenchymal origin (Saravanan et al., 2015).
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Download PDF- A.B. De Nardi, Rio de Janeiro, Roca, pp 500-505. Das, U., & Das, A.K. (2000). Review of canine transmissible venereal sarcoma. Veterinary Research Communications, 24(8), 545-556. Flórez, M.M., Fêo, H.B., Da Silva, G.N., Yamatogi, R.S., Aguiar, A.J., Araújo Jr, J.P., & Rocha, N.S. (2017). Cell cycle kinetics, apoptosis rates and gene expressions of MDR-1, TP53, BCL-2 and BAX in transmissible venereal tumour cells and their association with therapy response. Veterinary and Comparative Oncology, 15(3), 793-807.
- Jadhao, A., Baba, O.K., & Gupta, K. (2022). Cytopathology of extragenital transmissible venereal tumour in a dog. Indian Journal of Veterinary Science and Biotechnology, 18(1), 129-132.
- Kim, J., Kwon, S.Y., Cena, R., Park, S., Oh, J., Oui, H., & Choi, J. (2014). CT and PET-CT of a dog with multiple pulmonary adenocarcinoma. Journal of Veterinary Medical Science, 76(4), 615-620.
- Kumbhani, T.R., Fefar, D.T., Bhadaniya, A.R., Trangadia, B.J., Kalaria, V.A., & Padaliya, N.R. (2022). Extra-genital canine transmissible venereal tumor investigation using cytology, histopathology, and immunohistochemistry. Indian Journal of Veterinary
- Pathology, 45(2), 158-161.
- Leil, A.Z., El-Rahman, A., & and Howida, M.A. (2022). Clinical response of dogs affected with transmissible venereal tumor (TVT) to the chemotherapeutic regime with regard to cytomorphology and histopathology. Journal of Applied Veterinary Science, 7(2), 58-65.
- Luna, A.G. (1968). Manual of Histological and Special Staining Techniques. 3rd edn., Armed Forces Institute of Pathology, McGrawhill Book Co., London.
- Panchkhande, N., Dewangan, R., Kalim, M.O., Sharda, R., Ratre, H.K., Sahu, D., & Yadav, S.K. (2019). Incidence of mammary tumour and venereal granuloma in canine in Durg District Chhattisgarh. International Journal of Current Microbiology and Applied Sciences, 8(4), 2368-2381.
- Rugmini, K.S., Subapriya, S., Raj, P.H., Rao, G.V.S., & Ramesh, S. (2025). Canine ocular transmissible venereal tumour: A report of four cases. The Indian Journal of Veterinary Sciences and Biotechnology, 21(1), 133-136.
- Saravanan, M., Shafiuzama, M., Ranjithkumar, M., Raj, H.P., Satheskumar, S., & Saahithya, R. (2015). Generalized cutaneous and genital form of transmissible venereal tumor in a Mongrel dog and its therapeutic management. International Journal of Current Research, 7(1), 11586-11589.
- Sritrakoon, N., Maneesaay, P., Kasorndorkbua, C., Supreeya, S., Charuwan, W., Sunee, K., & Aree, T. (2020). Intraocular transmissible venereal tumours in dogs: A retrospective review of 21 cases. Journal of Food Science and Technology,
- 42(3), 608-614.
- Tella, M.A, Ajala, O.O., & Taiwo, V.O. (2004). Complete regression of transmissible venereal tumor in Nigerian Mongrel dogs with vincristine sulphate chemotherapy. African Journal of Biomedical Research, 7, 133-138.
- Valençoela, R.A., Antunes, T.R., Sorgatto, S., Oliveira, B.B., Da Silva Godoy, K.C., & De Souza, A.I. (2015). Cytomorphological aspects and frequency of canine transmissible venereal tumour subtypes in the municipality of Campo Grande, MS, Brazil. Acta Veterinaria Brasilica, 9(1), 82-86.
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