Skip to content
Home▶ Journals▶ Indian Journal of Veterinary Sciences and Biotechnology▶Archive▶Vol. 20 No. 5 (2024)▶Radiographic Evaluation of Bioglass and…
Indian Journal of Veterinary Sciences and Biotechnology
Indian Journal of Veterinary Sciences and Biotechnology ›
Print ISSN 2394-0247 · Online ISSN 2395-1176
Submit your paper About the journal
Research Article

Radiographic Evaluation of Bioglass and Polymethylmethacrylate for Long Bone Fracture Repair in Dogs

, , , , ,
Rutuja Sawant — Department of Veterinary Surgery and Radiology, Mumbai Veterinary College, Parel, Mumbai-400012, Maharashtra Animal and Fishery Sciences University, Nagpur, India
Girish Yadav — Department of Veterinary Surgery and Radiology, Mumbai Veterinary College, Parel, Mumbai-400012, Maharashtra Animal and Fishery Sciences University, Nagpur, India
Dinesh Lokhande — Department of Veterinary Surgery and Radiology, Mumbai Veterinary College, Parel, Mumbai-400012, Maharashtra Animal and Fishery Sciences University, Nagpur, India
Gajendra Khandekar — Department of Veterinary Surgery and Radiology, Mumbai Veterinary College, Parel, Mumbai-400012, Maharashtra Animal and Fishery Sciences University, Nagpur, India
Harshal Patil — Department of Veterinary Surgery and Radiology, Mumbai Veterinary College, Parel, Mumbai-400012, Maharashtra Animal and Fishery Sciences University, Nagpur, India
Dishant Saini — Department of Veterinary Surgery and Radiology, Mumbai Veterinary College, Parel, Mumbai-400012, Maharashtra Animal and Fishery Sciences University, Nagpur, India
Published 7 Sep 2024 Vol. 20 No. 5 (2024), pp. 138-142 ● Open access
❝ How to cite 🔗 https://doi.org/10.48165/ijvsbt.20.5.27
Download PDF

Abstract

Long bone fracture fixation with various techniques, viz., internal fixation, external fixation, external coaptation has been adapted since  long time in veterinary practice. Despite of such advancements complications like implant loosening, migration resulting in malunion,  non-union and delayed union are being observed later on. Various biomaterials have been identified and used in fracture management to  improve the implant stability by holding bone and implant in position, enhancing and accelerating the bone healing via callus formation.  Bioglass and Polymethylmethacrylate (PMMA) bone cement are a few of the biomaterials being used in the veterinary orthopaedics.  This study was conducted on clinical cases of long bone fracture repair in 12 dogs, divided equality into two groups. Group I dogs  were treated with Locking Compression Plate with bioglass putty as filling agent at interfragmentary spaces, while those in Group II  were treated with Locking Compression Plate with PMMA as filling agent at interfragmentary spaces. The bone formation and bone  union scores were significantly improved at 15th, 30th and 60th day interval of observation in both the groups. There was no statistically  significant difference in scores between two groups, yet the scores were found to be better in group I, which might be attributed to  the osteostimulative and osteoconductive properties of bioglass bone cement. PMMA bone cement is non-biodegradable and has  numerous potential uses, but has serious disadvantages due to its adverse effects also

KeywordsBioglassDogsLocking compression platingLong bone fracturePMMA bone cement

The full text of this article is available as a PDF.

Download PDF
  1. Brandi, M.L. (2012). Drugs for bone healing. Expert Opinion on Investigational Drugs, 21(8), 1169-1176.
  2. Chai, F., Raoul, G., & Wiss, A. (2011). Bone substitutes: Classification and concerns. Revue de Stomatologie, de Chirurgie Maxillo Faciale et de Chirurgieorale, 112(4), 212-221.
  3. Fujishiro, Y., Hench, L.L., & Oonishi, H. (1997). Quantitative rates of in vivobone generation for Bioglass® and hydroxyapatite particles as bone graft substitute. Journal of Materials Science: Materials in Medicine, 8(11), 649-652.
  4. Gadhafi, P., Devanand, C.B., John Martin, K.D., Syam, K.V., & Lucy, K.M. (2016). Clinical evaluation of bioglass for augmenting fracture healing in dogs. Journal of Veterinary and Animal Sciences, 47(2), 47-50.
  5. Krishnan, V., & Lakshmi, T. (2013). Bioglass: A novel biocompatible innovation. Journal of Advanced Pharmaceutical Technology & Research, 4(2), 78-83.
  6. Lane, J.M., & Sandhu, H.S. (1987). Current approaches to experimental bone grafting. Orthopedic Clinics of North America, 18(2), 213-225.
  7. Langley-Hobbs, S. (2003). Biology and radiological assessment of fracture healing. In Practice, 25(1), 26-35.
  8. Larsson, S. (2006). Cement augmentation in fracture treatment. Scandinavian Journal of Surgery, 95, 111-118.
  9. Moimas, L., Biasotto, M., & Di, L.R. (2006). Rabbit pilot study on the resorbability of three-dimensional bioactive glass fibre scaffolds. Acta Biomaterialia, 2, 191-199.
  10. Nandi, S.K., Roy, S., & Mukherjee, P. (2010). Orthopaedic applications of bone graft and graft substitutes: A review. Indian Journal of Medical Research, 132, 15-30.
  11. Neo. M., Nakamura, T., & Ohtsuki, C. (1994). Ultrastructural study of the A-W GC-bone interface after long-term implantation in rat and human bone. Journal of Biomedical Materials Research, 28, 365-372.
  12. Ranjan, R.K., Kumar, M., Kumar, R., & Ali, M.F. (2017). Bone Cement. International Journal of Orthopaedic Sciences, 3(4), 79-82. Vaishya Raju, Chauhan Mayank, & Vaish Abhishek (2013). Bone cement,
  13. Journal of Clinical Orthopaedics and Trauma, 4(4), 157-163. Välimäki, V.V., Yrjans, J.J., Vuoriom, E.I., & Aro, H.T. (2005). Molecular biological evaluation of bioactive glass microspheres and adjunct bone morphogenetic protein 2 gene transfer in the enhancement of new bone formation. Tissue Engineering, 11 (3-4), 387-394.
  14. William, R., Moore, Stephan, E., Graves, S., & Gregory, I. (2001). Synthetic bone graft substitutes. New Zealand Journal of Surgery, 71, 354-361.

Looking up citing articles…

    Creative Commons License

    This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

    Copyright © 2024 Indian Journal of Veterinary Sciences and Biotechnology