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Indian Journal of Veterinary Sciences and Biotechnology
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Research Article

Comparative Anaesthetic Effects of Propofol and Tiletamine- Zolazepam Anaesthetic Agents in Dogs

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Sunnykumar H Zalavadiya — Department of Veterinary Surgery and Radiology, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat-362 001, India
Jignesh V Vadalia — Department of Veterinary Surgery and Radiology, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat-362 001, India
Arshi A Vagh — Department of Veterinary Medicine, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat-362 001, India
Raghuvir H Bhatt — Department of Veterinary Clinical Complex, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat-362 001, India
Shivaji H Talekar — Department of Veterinary Surgery and Radiology, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat-362 001, India
Vaibhavsinh D Dodia — Department of Veterinary Surgery and Radiology, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat-362 001, India
Monaliben B Bhesaniya — Department of Veterinary Anatomy, College of Veterinary Sciences and Animal Husbandry, Kamdhenu University, Junagadh, Gujarat-362 001, India
Published 10 May 2024 Vol. 20 No. 3 (2024), pp. 153-157 ● Open access
❝ How to cite 🔗 https://doi.org/10.48165/ijvsbt.20.3.30
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Abstract

The study evaluated two different anaesthetic protocols in dogs (n=24) for anaesthetic parameters like dose of anaesthetic agents for  induction and maintenance of anaesthesia, quality of sedation, induction, maintenance of anaesthesia and recovery. All the animals were  first premedicated with butorphanol @ 0.2 mg/kg b.wt. and xylazine @ 1 mg/kg b.wt., i/m, simultaneously. After 15 min of preanaesthetic  medication, induction and maintenance of anaesthesia was achieved by administration of propofol @ 3 mg/kg b.wt., i/v in Group-I  (n=12) and tiletamine-zolazepam @ 2 mg/kg b.wt., i/v in Group-II (n=12). Both protocols showed excellent quality of induction and  maintenance of anaesthesia in the all animals. Physiological parameters like heart rate, respiration rate, rectal temperature and blood  saturation of oxygen altered at different time intervals during the anaesthesia, but remained in normal physiological range. Xylazine  and butorphanol preanesthetics showed dose sparing effect on induction and maintenance dose of propofol. Propofol resulted in  excellent recovery quality and shorter recovery time compared to tiletamine-zolazepam.  

KeywordsButorphanolDogPropofolTiletamine-ZolazepamXylazine

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