Comparing and Evaluating the Effects of Suprelorin and Omega-3 on Male Rabbit Hormones
DOI:
https://doi.org/10.48165/ijapm.2026.42.SI.17Keywords:
Rabbit, Castration, testosterone, Omega-3, and Suprelorin.Abstract
The goal of the current study was to examine how Omega-3 and Suprelorin affect the levels of testosterone, FSH, and ICSH. In this study, 20 male rabbits were given large doses of Omega-3 (9 ml) and Suprelorin (0.3 cc) to assess the impact of these substances on histology. The rabbits were divided into four groups: T1 stands for control, T2 for castration, T3 for omega-3, and T4 for supralorin. Blood samples were collected, and a hormonal assay was performed to measure the levels of FSH (IU\L), ICSH (IU\L), and testosterone in each plasma sample on 0, 15th, and 30th days. The testes were removed from the rabbits for histological analysis. In the T2 group, after bilateral castration, testosterone levels were considerably (p<0.05) lower 15 and 30 days later. In 30 days, the rabbits’ serum FSH (IU\L) levels were significantly lower (0.12 ±0.009) than those of the control group (2.10±0.46). In the T3 group, the highest dose of Omega-3 (9ml) was the only one that affected the rabbits’ testes more than the 15–30 days (0.025±0.0027 and 0.015±0.0012), significantly increasing the testosterone level in the control group (6.21±0.87). In the T4 group, testosterone levels in male rabbits treated with Deslorelin (Suprelorin) rose significantly (P<0.05) in the control group to 4.81±0.81 ng/dl, compared to 0.048±0.0073 and 0.037±0.0073 ng/dl after 15 and 30 days. We conclude that the single, slow-release implant containing 4.7 mg deslorelin permanently and reversibly inhibited the male rabbit’s sexual function. However, omega-3 polyunsaturated fatty acids (PUFAs) can prevent increased testosterone levels, making them a potential contraceptive in rabbits.
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