Advances in Applied Biological Research
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description: Advances in Applied Biological Research is an esteemed open-access journal dedicated to the swift dissemination of high-impact research in the field of applied biological sciences. Our mission is to advance knowledge and innovation across various applied biological disciplines by publishing original, high-quality research that addresses real-world challenges and contributes to scientific and practical advancements. Scope: The journal covers a broad spectrum of applied biological fields, including: Agriculture: Research focused on improving crop yield, pest management, and sustainable farming practices. Veterinary Sciences: Studies related to animal health, disease management, and veterinary advancements. Medical Sciences: Innovative research on diagnostics, treatment methods, and biomedical applications. Ecology and Environmental Sciences: Investigations into ecosystem dynamics, environmental conservation, and climate change impacts. Biotechnology: Cutting-edge research in genetic engineering, molecular biology, and biotechnological applications. Biochemistry: Advances in understanding biological processes at a molecular level, including enzymology and metabolic pathways. Key Features: Original Research Papers: Detailed studies that contribute novel findings and advance the field. Short Communications: Brief reports on significant or timely findings that offer insights into emerging trends. Review Articles: Comprehensive reviews providing critical overviews of specific topics within applied biological research, synthesizing current knowledge, and identifying future research directions. Technical Notes: Reports on innovative techniques or methodologies that enhance research practices and applications. Peer Review Process: All manuscripts submitted to Advances in Applied Biological Research undergo a stringent double-blind peer-review process to ensure the highest standards of scientific quality and integrity. Our expert reviewers evaluate submissions based on their o…
publisher: ACS Publisher
language: en
publication name: Advances in Applied Biological Research
issn: 3048-9261
items: Role of Plant Resources in Livelihood Security and Cultural Traditions of the Gond Tribe in Mohla-manpur-chowki District, Chhattisgarh
items: Strategic nutritional enhancement in Rabi Pulses: A pragmatic breeding approach
items: Green Synthesis of Cu–ZnO Nanocomposite Using Pomegranate Peel Mesocarp Extract for Controlling Xanthomonas Campestris Causing Bacterial Blight in Tomato
items: Cell Phone Tower Radiations And Associated Health Hazards In Hilla City, Babylon, Iraq
items: Morphological and Chemical Characterization of Aconitum heterophyllum, a Critically Endangered Himalayan Medicinal Plant
items: Computational Evaluation Of Phytochemicals In Multi-Targeted Therapy Against AML And CML: A Molecular Docking And Drug-Likeness Study
items: Role of Cystatin C as Early Predictor of Renal Dysfunction in Iron Overloaded Beta Thalassemia Major Patients
items: The Untold History Of Pakistan’s Poultry Industry: A Review
items: Integrating Ayurvedic Therapies in Chronic Kidney Disease Management: A Case Report on Symptom Improvement and Renal Function Enhancement
items: Effectiveness of Ayurvedic and Panchakarma Therapies in Managing Chronic Kidney Disease: A Case Study Report
items: A Review on Hybrid Closed Loop Insulin Delivery System
items: Evaluation of cardio protective Phytochemicals from Phyllanthus maderaspatensis- an in vitro, in vivo and in silico approach
items: Green synthesis and characterization of Zinc oxide nanoparticle with polyspice extractantioxidant and antibacterial potential against oral pathogens
items: Study on Biomedical activity of stem and leaf extraction of Heliotropium marifolium (J. Kocnig ex Retz.)
items: Sustainable Food Systems in India: A Pathway to Overcoming Food Insecurity
items: Evaluation of Bone Mineral Density among elderly Type II Diabetes Mellitus Patients in Babil 2025
items: Worldwide Risk Analysis of Brain Tumours in Young Adults and Adolescents
items: Tinospora cordifolia GCMS profiling and cytotoxic effect on HCT 116- In vitro assay
items: A Comprehensive Review Of Multi-Omics, Network Pharmacology, And Artificial Intelligence Approaches To Heart Failure
items: Unraveling Human Metapneumovirus: A Full-Spectrum Review Of Its History, Global Burden, Bioinformatics Advances, And Current Gaps
items: The Heritage on Our Plates: Reviving Traditional Diets for Modern Wellbeing
items: Deep Vein Thrombosis associated with Cesarean Delivery: An Overview Illustrative Study
items: Risk for Diabetic Foot Ulcer Associated with Type 2 Diabetes Mellitus Patients
items: Role of Vitamin C in Health and Disease: A Comprehensive Review
items: Role of DIP Diet in Managing Blood Transfusion-Dependent Thalassemia Major: A Case Study of Integrative Therapies”
items: Evaluating the Efficacy of Ayurvedic Treatments in Stage V Chronic Kidney Disease: A Case Report
items: Exploring the Versatility of Bacillus spp. Secondary Metabolites: its mode of action and application in various field
items: Ethnomedicinal Plant Treatment Practices in Vouge for Curing Different Ailments in the Villages of Alluru Sitarama Raju District, the Eastern Ghats of Andhra Pradesh, India
items: Molecular Identification of Family Colubridae from Punjab, Pakistan
items: Isolation and Identification of Bacteria from the Oral Cavity of Monitor Lizard (Varanus bengalensis)

Role of Plant Resources in Livelihood Security and Cultural Traditions of the Gond Tribe in Mohla-manpur-chowki District, Chhattisgarh
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description: The present study was conducted to document the traditional knowledge and utilization of plant resources by the Gond tribe inhabiting Chiharitola village of Mohla-Manpur-Chowki district, Chhattisgarh, India. The study aimed to assess the knowledge and use of local plant species in relation to livelihood, healthcare, food, rituals, handicrafts, and other socio-cultural practices. Field investigations were carried out from January to March 2024 using ethnobotanical survey methods, including structured questionnaires, interviews with knowledgeable elders, village leaders (Gayta), field observations, group discussions, and plant specimen documentation. Plant species were identified using standard floristic literature and verified with the assistance of local informants. The investigation documented a total of 50 plant species belonging to 20 families. Among these, 20 species were utilized for livelihood security and non-timber forest products, 8 species for ritual and cultural ceremonies, 8 species for traditional medicinal purposes, 5 species as cultivated crops, 4 species as wild edible resources, 3 species as host plants for lac production, 3 species for gum collection, and 2 species for residential construction. The families Fabaceae, Poaceae, Combretaceae, Sapotaceae, and Anacardiaceae were found to be the most dominant and economically important. Various plant parts, including fruits, seeds, leaves, flowers, stems, bark, and tubers, were used for food, medicine, handicrafts, construction, and income generation. The study revealed that non-timber forest products such as mahua (Madhuca longifolia), tamarind (Tamarindus indica), char (Buchanania lanzan), tendu (Diospyros melanoxylon), honey, lac, and gums play a significant role in supporting the livelihoods of tribal households. Several plant species were also found to be closely associated with traditional rituals, including birth ceremonies, marriages, Nawakhai celebrations, and funeral rites. Medicinal plants suc…
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creator: Devendra Nirmalkar
creator: Daneshwar Prasad
creator: Vijay Laxmi Naidu
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-07-03
publication date: 2026-07-03
starting page: 20
ending page: 33
doi: 10.48165/aabr.2026.3.02.03

Strategic nutritional enhancement in Rabi Pulses: A pragmatic breeding approach
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description: Rabi pulses like chickpeas (Cicer arietinum L.), lentils (Lens culinaris Medik.), pigeonpeas (Cajanus cajan L.), and cowpeas (Vigna unguiculata L.) serve as fundamental sources of protein, iron, zinc, and dietary fiber. Nonetheless, antinutritional factors (ANFs) including phytic acid, tannins, protease inhibitors, and raffinose family oligosaccharides impede nutrient absorption. This study encapsulates the molecular mechanisms underlying protein biosynthesis, encompassing seed storage protein accumulation, nitrogen assimilation via GS/GOGAT, and essential transcriptional regulators involved in seed development. Emphasis is placed on protein bioavailability rather than mere accumulation, with a focus on strategies to mitigate ANF synthesis through genomics-assisted breeding. Advanced techniques such as CRISPR/Cas9 gene editing, quantitative trait loci (QTL) mapping, and genome-wide association studies (GWAS) have been employed to identify promising targets for reducing ANFs and bolstering nutritional content. The integration of contemporary breeding approaches with processing techniques presents a viable pathway to cultivate nutritionally enhanced and climate-resilient pulse varieties, thereby supporting global food security and nutritional health.
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creator: Hemanth C N
creator: Thanga Hemavathy A
creator: Shanmugam P S
creator: Sundaralingam K
creator: Kumar M
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-07-07
publication date: 2026-07-07
starting page: 34
ending page: 48
doi: 10.48165/aabr.2026.3.02.04

Green Synthesis of Cu–ZnO Nanocomposite Using Pomegranate Peel Mesocarp Extract for Controlling Xanthomonas Campestris Causing Bacterial Blight in Tomato
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description: Zinc oxide/copper (ZnO/Cu) nanoparticles were synthesized using a green synthesis method based on pomegranate pulp peel extract. The purpose of the study is to manufacture an environmentally friendly zinc and copper oxide nanocomposite using plant residues from pomegranate pulp peel extract, and to use it to combat bacterial blight in tomatoes. The synthesized sample was examined to characterize the nanoparticles using UV-Vis spectroscopy, energy dispersive spectroscopy (EDS), field-emission scanning electron microscopy (FE SEM), and X-ray diffraction (XRD).The observed peak at 480 nm in the surface plasmon resonance of the zinc oxide nanoparticles indicated the formation of nanoparticles of varying sizes, both large and small. The successful synthesis of the compound was inferred from the shift in the UV-Vis absorption peaks using pH, time, concentration, copper-to-zinc oxide ratio, and temperature. X-ray diffraction (XRD) and phase morphology analysis revealed the crystalline nature of the nanoparticles. The average crystal size of the ZnO nanoparticles synthesized using the extract and ZnO/Cu nanocomposites was 24.16 nm, representing the highest point in the halo. However, this is not considered a sharp “crystalline peak,” and the presence of sharp peaks at angles of 25.85, 29.45, and 31.85 is strong evidence of a regular atomic arrangement. Morphological analysis of the synthesized nanoparticles using high-resolution electron microscopy (HR-TEM) revealed an irregular to nearly spherical shape with sizes ranging from 10 to 200 nm.
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creator: Ban Mohammed Hussein Ali
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-05-23
publication date: 2026-05-23
starting page: 12
ending page: 19
doi: 10.48165/aabr.2026.3.2.02

Cell Phone Tower Radiations And Associated Health Hazards In Hilla City, Babylon, Iraq
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description: Background: The obvious increase in mobile phone base stations in Iraq after the year 2003 has raised worries about potential nonspecific health symptoms affected by electromagnetic radiation produced. Studies on this issue in Iraq were scarce. Objective of the study: To identify the possible nonspecific health problems among adult inhabitants who lived for five years or more at a distance of up to 300 meters from mobile phone base stations and towers compared to those who lived far away from cell phone towers (500 meters and more). Methods: A cross sectional descriptive study was conducted in Hilla city, Babylon province, during the period from November 2017 through February 2018. A non-probability (purposive sample) was selected from populations living in AL-Hilla urban regions for more than five years close to four randomly selected base station towers and those who lived in areas more than 500 meters from the same cell towers. A convenience sample constituted 278 adults aged 18 years and above of both sexes who were investigated after obtaining their verbal consent and who had completed a pretested questionnaire that focused on the subjective symptoms they suffered from via in-depth face-to-face interviews. Results: The findings of the current study revealed a statistically significant increase in ill-health effects (prevalence of nonspecific symptoms) <0.05 among those living in the locality <300 meters from mobile telephone base stations compared to those who lived far away from the mobile phone stations >500 meters. The strongest associations (<0.01) were fatigue, headache, sleeping disorders, difficulty in concentration, and dizziness. The male-to-female ratio in this study was 1.5:1. The social problems related to this health issue included that only one in five of the participants mentioned that they were informed before setting the stations near their houses, and 75% of inhabitants near the stations reported conflicts with the owner of the building where …
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creator: Zaid Abdullah Hussain
creator: Hasan Alwan Baiee
creator: Zainab Abdulameer Abdulrasol
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-05-14
publication date: 2026-05-14
starting page: 57
ending page: 63
doi: 10.48165/aabr.2026.3.1.06

Morphological and Chemical Characterization of Aconitum heterophyllum, a Critically Endangered Himalayan Medicinal Plant
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description: Aconitum heterophyllum Wall. ex Royle is a critically endangered Himalayan medicinal herb extensively used in traditional medicine for its analgesic, antipyretic, and anti-inflammatory properties. The present study evaluated the species through morphological characterization, qualitative phytochemical screening, and GC– MS profiling of methanolic root extracts. Morphological observations confirmed diagnostic features such as paired tuberous roots, palmately lobed leaves, and racemose inflorescences, supporting species authentication. Preliminary phytochemical analysis revealed the presence of alkaloids, carbohydrates, lipids/ fatty acids, and phenolic compounds, whereas flavonoids and saponins were absent. GC–MS analysis identified ten major compounds, predominantly α-linolenic acid, palmitic acid, fatty acid esters, carbohydrate derivatives, and nitrogen-containing metabolites. The findings indicate a chemically diverse metabolite profile with potential antioxidant and anti-inflammatory significance. However, the study also recognizes the limitations of GC–MS in detecting thermolabile diterpenoid alkaloids characteristic of Aconitum species. Overall, the study establishes baseline pharmacognostic and chemical markers useful for authentication, quality evaluation, conservation planning, and future LC–MS/MS- based metabolomic investigations of this threatened Himalayan medicinal plant.
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creator: Mir Muskan Un Nisa
creator: Ishtiyak Ahmad Peerzada
creator: Sajad Ahmad Gangoo
creator: Parvez Ahmad Sofi
creator: Talib Bashir Bhat
creator: Sourav Singh
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-05-23
publication date: 2026-05-23
starting page: 1
ending page: 11
doi: 10.48165/aabr.2026.3.2.01

Computational Evaluation Of Phytochemicals In Multi-Targeted Therapy Against AML And CML: A Molecular Docking And Drug-Likeness Study
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description: Background and Rationale: Acute Myeloid Leukemia (AML) and Chronic Myeloid Leukemia (CML) are different blood cancers. They face critical treatment challenges, mainly drug resistance, such as the BCR-ABL1 T315I mutation, and the presence of Leukemic Stem Cells (LSCs). In India, CML occurs at a much younger age, creating an urgent need for cost-effective and safe alternatives to standard Tyrosine Kinase Inhibitors (TKIs). Research Aim: This study aims to use detailed computational (in-silico) methods to find and assess effective phytochemicals that can serve as multi-target inhibitors. The main goal is to discover natural compounds that can bypass known resistance mechanisms in CML and AML while effectively targeting pathways crucial for LSC survival, such as PP2A and HIF-1. Methodology: The research uses a high-throughput virtual screening strategy. Molecular docking simulations evaluate the binding strength and suitability of phytochemical libraries against key resistance targets (BCR-ABL1 T315I, FLT3) and LSC regulators. At the same time, we conduct ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiling and drug-likeness assessment (Lipinski’s Rule of Five) to prioritize compounds with good oral bioavailability and safety profiles suitable for long-term treatment. Conclusion: This study applies polypharmacology to demonstrate how phytochemicals can function as effective multi-target therapeutic leads. By moving beyond the traditional “one-drug-one target” approach, these natural bioactive compounds provide a strategic way to bypass drug resistance and eliminate the resilient leukemic stem cell populations that drive relapse in AML and CML.
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creator: Sayan Mukherjee
creator: Vaibhav Sable
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-05-13
publication date: 2026-05-13
starting page: 50
ending page: 56
doi: 10.48165/aabr.2026.3.1.05

Role of Cystatin C as Early Predictor of Renal Dysfunction in Iron Overloaded Beta Thalassemia Major Patients
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description: Background: Beta thalassemia major patients are at risk to developing renal dysfunction over a period of time, secondary to chronic anemia, iron overload and chelation therapy. Early observation of renal insufficiency is necessary for intervention. Objectives: The objective of this study was to assess the value of cystatin c as an early marker of renal dysfunction in pediatric patients with iron overload Beta thalassemia major and investigates the related clinical factors. Patients and Methods: This was a cross sectional study which was conducted in Babylon center for hereditary blood disorders in Babylon governorate, 74 patients with beta thalassemia major whose parents accepted to participate in this study. Data collection was done by direct interview with parents. It was done by using performed questionnaire and tested for epidemiological and clinical factors. The concentration of cystatin C, creatinine, ferritin and haemoglobin were determined. Apparent correlations with cystatin C were analyzed for several factors, including age, age at presentation, duration of the disease, age at first blood transfusion and compliance with therapy and then take blood sample and examine the patient height. Results: A total of 74 patients with beta thalassemia major were enrolled in this study. Cystatin C adjusted concentrations showed a trend to increase with the later age at diagnosis (P < 0.0001); patients with diagnosis by 3-5 years were found the highest (1.42 ± 0.230 mg/L) compared to those diagnosed earlier at < 1 year (1.08 ± 0.248 mg/L) or between 1-3 years (1.11 ± 0.201 mg/L). Age at the first blood transfusion (P = 0.001) and therapy adherence (P = 0.032) were significantly associated with cystatin C levels and were higher in the non adherence group. Correlation of cystatin C was statistically in significant with serum creatinine (P = 0.047) while no correlation with age (P = 0.476) and duration of disease (P = 0.7) was observed unlike creatinine. There was significa…
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creator: Tamarra Haider Dheya
creator: Ahmed Abdul-Mohsin Alshammary
creator: Ammar Hatem Abdullateef
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-04-03
publication date: 2026-04-03
starting page: 29
ending page: 39
doi: 10.48165/aabr.2026.3.1.03

The Untold History Of Pakistan’s Poultry Industry: A Review
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description: Birth of Pakistan’s poultry industry is often attributed to the sole collaboration of Pakistan’s International Air lines- PIA with that of Canada’s Messer Shaver’s Shaver Breeding Farms. In this way, the role of the Government of Pakistan and Britian Era’s Institutions, in the late 1940s, has been overlooked altogether. In addition, the vital role played by worthy foreign and local investors e.g., Lever’s Brothers, Arber Acres Private Limited, Packages Limited, has always been undermined while unfolding the history of Pakistan poultry industry. This paper is a humble effort to put some light on hidden gems of Pakistan’s poultry industry. By particularizing their part in framing a strong poultry industry in Pakistan, it is an attempt to express our appreciations towards these pioneers.
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creator: Muhammad Waqas
creator: Jibran Hussain
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-12-31
publication date: 2025-12-31
starting page: 67
ending page: 75
doi: 10.48165/aabr.2025.2.2.07

Integrating Ayurvedic Therapies in Chronic Kidney Disease Management: A Case Report on Symptom Improvement and Renal Function Enhancement
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description: Chronic kidney disease (CKD) affects 10–15% of adults globally and is often underdiagnosed due to limitations in standard serum creatinine assessments. This case report presents a 56-year-old male with a 1.5-year history of CKD and 5 years of hypertension, treated at Jeena Sikho Lifecare Limited Hospital, Derabassi, with a comprehensive Ayurvedic regimen including medicines and Panchakarma therapies. The patient showed marked improvement in multiple clinical parameters: pedal oedema decreased from grade 4˚ to 1˚, pain resolved completely (3/10 to 0/10), sleep quality improved from 3/10 to 7/10, and itching, initially rated 6/10, was fully alleviated. Vital signs stabilized, with blood pressure maintained at 120/80 mmHg, and body weight reduced from 82 kg to 73 kg, reflecting positive effects of lifestyle and dietary modifications. Laboratory investigations demonstrated gradual improvement and stabilization, with haemoglobin ranging from 7.1 to 9.3 gm/dL, urea decreasing from 200.85 mg/dL to 66.5 mg/dL, creatinine improving from 7.25 mg/dL to 5.61 mg/dL, and uric acid declining from 9.87 mg/dL to 6.87 mg/dL. Overall, the patient achieved normalization of clinical and laboratory parameters, highlighting the potential of Ayurveda as a safe, cost-effective, and integrative approach for managing CKD, particularly for patients seeking holistic healthcare solutions.
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creator: Acharya Manish
creator: Gitika Chaudhary
creator: Richa
creator: Suyash Pratap Singh
creator: Manjeet Singh
creator: Pooja
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-12-09
publication date: 2025-12-09
starting page: 49
ending page: 66
doi: 10.48165/aabr.2025.2.2.06

Effectiveness of Ayurvedic and Panchakarma Therapies in Managing Chronic Kidney Disease: A Case Study Report
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description: Chronic kidney disease (CKD) is defined as a progressive disease that affects the overall health of kidney. CKD is diagnosed in five stages based on its symptoms and the structure and function of kidney. CKD can be significantly influenced by several lifestyle factors. Poor dietary habits, such as high intake of salt, sugar, unhealthy fats, and processed foods, contribute to obesity, hypertension, and diabetes, key risk factors for CKD. Hence, the CKD treatment requires a multifaceted approach including adopting a healthy lifestyle with a balanced diet, regular exercise, stress management, and proper hydration. This case report focuses on a 31-year-old female patient with CKD for 2 years and hypertension for 6 months who received Ayurvedic treatment at Jeena Sikho Lifecare Limited Hospital, Derabassi. The treatment method administered on her was a combination of customized Ayurveda and Panchakarma therapies, resulting in significant progresses in her symptoms, kidney health and function, and general life quality. After 7 days of IPD, the patient showed improvement in Blood Urea and Serum Creatinine, also reported relief from periorbital swelling and other symptoms. This study highlights the potential of Ayurveda as an economical alternative to conventional treatments, especially for individuals with limited financial resources who face challenges in accessing advanced healthcare. While the results are encouraging, further research with larger randomized controlled trials is essential to assess the effectiveness and safety of Ayurvedic treatments for CKD.
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creator: Acharya Manish
creator: Gitika Chaudhary
creator: Richa
creator: Suyash Pratap Singh
creator: Manjeet Singh
creator: Pooja
creator: Tanu Rani
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-12-09
publication date: 2025-12-09
starting page: 35
ending page: 49
doi: 10.48165/aabr.2025.2.2.05

A Review on Hybrid Closed Loop Insulin Delivery System
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description: Type 1 diabetes mellitus (T1DM) is a habitual autoimmune condition taking lifelong insulin remedy. Conventional approaches like multiple quotidian injections or continuous subcutaneous insulin infusion are limited by hypoglycaemia trouble, glycaemic variability, and patientburden. Automated insulin delivery (AID) systems, particularly crossbred unrestricted- circle (HCL) systems, integrate continuous glucose monitoring, insulin pumps, and control algorithms to optimize insulin delivery. HCL systems automate rudimentary insulin and correction boluses, taking manual mess boluses, and haves hown significant benefits, including increased time- in- range (TIR), lower HbA1c, reduced hypoglycaemia, and enhanced quality of life. These benefits are seen across different populations, including children, grown- ups, and pregnant women. Despite these advancements, limitations remain, analogous as mess gelcap dependence, delayed post- mess glucose control, sensor delicacy issues, cost, and specialized malfunctions. fully unrestricted- circle systems are being developed to count manual input and further mimic physiological insulin regulation. With ongoing advances,HCL systems represent a significant step toward a fully independent artificial pancreas, offering bettered glycaemic control, safety, and quality of life for individualities with T1DM. These systems have the eventuality to revise diabetes operation and meliorate patientissues.
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creator: S G Kuralarasan
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-12-09
publication date: 2025-12-09
starting page: 25
ending page: 34
doi: 10.48165/aabr.2025.2.2.04

Evaluation of cardio protective Phytochemicals from Phyllanthus maderaspatensis- an in vitro, in vivo and in silico approach
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description: Background: Plants are used as complementary and alternative medicine for a variety of conditions, regardless of their crude or as their separated pharmacological components. The purpose of this study was to assess in vitro antioxidant and in vivo cardio protective of the Phyllanthus maderaspatensis. Methodology: Quantitative analysis and Gas Chromatography-Mass Spectrometry (GC-MS) phytochemical study based on solvent method of extraction were carried out. Using the conventional method of antioxidant assay among the leaf extract were ascertained. Isoproterenol (ISO)-treated rats were used for in vivo experiment to check the effect of plant extract on cardio protective bio markers. Results. There is an increased total antioxidant activity of extract found in a dose-dependent manner. At 50 μg, 19-24% activity and at 400 μg, 79-84% scavenging potential was recorded. The rats receiving the extract showed a decrease in heart weight and an increase in body weight. The mean concentration of cardiac troponin (cTn) T/I in the serum of rats treated with the standard drug reduced effectively (1.13±0.07/0.64±0.05 ng/mL), whereas significantly by the extract (1.25±0.19/0.72±0.08 ng/mL). The creatine kinase MB (CKMB) of the standard was significant at 78.33±6.26IU, and the extract was 83.35±7.51IU. The data showed increased values among the standard and extract compared to the control group but were found to be significantly (p < 0.001) decreased among the treated groups. Compared to negative control animals (healthy rats), isoproterenol (ISO)-treated rats had significantly increased levels of aspartate myocardial cell damage. After 5 weeks of treatment, in comparison to those in the positive control (PC), extract-treated rats had significantly (p <0.05) elevated levels of serum AST, alanine transaminase (ALT), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH). Recovery from ISO-induced electrophysiological abnormalities was confirmed by decreased serum cardioprotectiv…
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creator: Deepa B
creator: K C Venkatesh Babu
creator: M Shabana Begum
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-08-23
publication date: 2025-08-23
starting page: 25
ending page: 33
doi: 10.48165/aabr.2025.2.1.05

Green synthesis and characterization of Zinc oxide nanoparticle with polyspice extractantioxidant and antibacterial potential against oral pathogens
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description: Because it is environmentally beneficial, the synthesis of metal oxide nanoparticles utilizing medicinal plants is growing quickly. The polyspice extract made by soxhlet extraction with ethylacetate is used in this research to create zinc oxide nanoparticles. GCMS and qualitative phytochimcal analysis were carried out. ZnONP and extract antioxidant activities were measured and compared to a standard. Using the disc diffusion approach, an antibacterial experiment was conducted against oral pathogens. Polyspice was found to include alkaloids, flavonoids, and phenol. Ten distinct secondary compounds were detected using GCMS. UV-Vis Spectroscopy analysis was used to describe the synthesized NPs, with a peak detected at 396-398 nm. SEM with EDX analysis verified the NPs’ spherical form 30-98 nm and the primary constituents are oxygen and zinc. At 50–100 µg levels, ZnO NPs inhibition assay on DPPH, metal chelation, and hydroxyl radical activity demonstrates good inhibition against free radicals. The ZnONPs that were biosynthesized showed higher antibacterial effectiveness than the standard at least 25µg, which is equivalent to standard chlorohexidine. The pattern of the nanoparticles’ antibacterial activity against the chosen bacteria was P. gingivalis, S. mutans, and Fusobacterium sp. According to the study’s findings, synthesizing zinc oxide nanoparticles with a spice extract is an economical and environmentally responsible way to produce green ZnO nanoparticles that have strong anti-oxidant and anti-microbial properties against oral infections.
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creator: Nithyatharani R
creator: Abdul Farook S
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-12-09
publication date: 2025-12-09
starting page: 16
ending page: 24
doi: 10.48165/aabr.2025.2.2.03

Study on Biomedical activity of stem and leaf extraction of Heliotropium marifolium (J. Kocnig ex Retz.)
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description: New anti-diabetic compounds can be obtained from Indian herbal remedies, which are employed in the ancient Ayurvedic approach to manage hyperglycemia. A common medicinal plant, H. marifolium is a significant reservoir of compounds with potent antioxidant action. The main objective of the study was to find out the anti-inflammatory activities, antioxidant and antidiabetic effect of selected medicinal plant. Conventional parameters such as DPPH, ABTS, hydroxyl, superoxide radical, nitric oxide, and hydrogenperoxide assay were performed. The chromogenic iodine technique was used to quantitatively determine the activity of extracts in relation to amylase inactivation. At 250µg, the leaves extraction had a much stronger scavenge action (>75%) than the stem extraction (<75%). Both samples exhibited dose-related enhancements in antioxidant activity. When compared to its standard a low scavenging activity at 50µg concentration and comparable scavenging activity at 300µg was recorded among extract. One of the well-established roots of inflammation, protein denaturation, was successfully controlled by the use of the extract. Both extracts were discovered to have a non steroidal anti-inflammatory activity. Additionally antidiabetic study shows that the standard inhibitor, acarbose, has an least IC50 value of 122.37 μgml-1, following that the leaf and stem extracts (187.30 μg ml-1 and 209.26 μg ml-1, respectively). The data confirms that the primary compounds found in stem and leaf extracts may promote the effectiveness of antidiabetic, anti-inflammatory, and antioxidant nature of the plant.
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creator: S Nithya
creator: E G Wesely
creator: Helan Soundra Rani Michael
creator: M Shabana Begum
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-08-23
publication date: 2025-08-23
starting page: 34
ending page: 38
doi: 10.48165/aabr.2025.2.1.06

Sustainable Food Systems in India: A Pathway to Overcoming Food Insecurity
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description: With a population of 1.43 billion, India surpassed China in 2023 to become the most populous country, accounting for nearly 18% of the world’s total population. This surge has raised major concerns, including increased pressure on natural re sources, rising unemployment, strain on healthcare and education systems, urban overcrowding and environmental degradation. One of the most pressing challeng es is ensuring sustainable food systems that can meet the nutritional needs of this vast population without compromising the environment. Despite major advance ments in India’s agricultural sector and a rise in food crop production, the nation continues to face challenges in ensuring a sufficient food supply for its entire pop ulation. Many Indians continue to experience food insecurity and hunger, contrib uting to the double burden of malnutrition, marked by a high prevalence of under nutrition alongside a growing incidence of obesity, largely driven by poor dietary quality. Given these challenges, transitioning to a sustainable food system is not just desirable but essential for India. A sustainable food system has the potential to simultaneously improve nutrition, protect the environment, support livelihoods and ensure equitable access to food. However, achieving this requires addressing systemic obstacles while leveraging the opportunities offered by innovation, tradi tional knowledge and policy reform. This review aims to explore the current status of India’s food system, examine the opportunities for promoting sustainability and identify key barriers that hinder progress.
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creator: Khyati Joshi
creator: Sarla Lakhawat
creator: Alok Kumar Saini
creator: Harshita Bordia
creator: Prerna Shekhawat
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-08-16
publication date: 2025-08-16
starting page: 17
ending page: 24
doi: 10.48165/aabr.2025.2.1.04

Evaluation of Bone Mineral Density among elderly Type II Diabetes Mellitus Patients in Babil 2025
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description: Background: Type 2 diabetes mellitus is associated with various complications, including potential impacts on bone health. Although elderly patients with Type 2 diabetes mellitus may exhibit normal bone mineral density they are paradoxically at a higher risk for fractures. The underlying mechanisms remain multifactorial, involving glycaemic control, hormonal regulation, and nutrient deficiencies. Objective: To evaluate bone mineral density in elderly patients with Type 2 diabetes mellitus and investigate its relationship with glycaemic control, vitamin D levels, and calcium status.Patients and Methods: A prospective, cross-sectional study was conducted on 46 patients above 65 years of age in Merjan teaching hospital babil, Iraq, from May 2024 to May 2025. Data collected included demographics, HbA1c levels, serum vitamin D and calcium, and bone mineral density measured via DEXA scans at the spine and hips. Results: Osteoporosis was present in 54.3% of patients, with 34.8% of patients were classified as osteopenic. The majority of patients were females. A positive correlation was found between HbA1c and DEXA scan T-scores (r = 0.313, p = 0.034), patients with poor glycaemic control (mean HbA1c = 9.2%) had a higher prevalence of osteoporosis. No significant correlations were found between bone mineral density (Dexa T-scores) and serum vitamin D (r = -0.057, p = 0.705) or calcium levels (r = -0.080, p = 0.597). The right hip showed the highest site-specific prevalence of osteoporosis (41.3%).Conclusions: Osteoporosis is highly prevalent among elderly patients, particularly women. Poor glycemic control (high HbA1c) and increasing age are significantly associated with lower bone density. Recommendation: DEXA scans of multiple sites, especially the spine and hips, are essential for detecting osteoporosis in this population.
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creator: Abdulmuttaleb Abduljabbar Fayyadh
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-08-06
publication date: 2025-08-06
starting page: 6
ending page: 11
doi: 10.48165/aabr.2025.2.1.02

Worldwide Risk Analysis of Brain Tumours in Young Adults and Adolescents
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description: In those under 20, the most common solid malignancies are brain tumours, which account for most of cancer-related deaths. By gathering information from institutional series, population-based studies, and case-control investigations done all throughout the world, this review examines the weight, incidence, and risk elements related with brain tumours in children and adolescents. Recent epidemiological data from countries like Finland, Canada, the United States, China, and Korea points to an annual incidence rate among young people ranging from 3.5 to 5. 1 case per 100,000, with the highest rates observed among youngsters aged 0 to 4. Among the most frequent tumour types are pilocytic astrocytoma, medulloblastoma, ependymoma, aberrant teratoid/rhabdoid tumours, and medulloblastoma. Studies show small local variations in the incidence of tumour types; germ cell tumours are somewhat more common in Asian populations and show a slight male bias. This review focuses on brain tumour in the young population it’s a subject of growing medical and public health concern, this evaluation emphasizes the essential need of continuous monitoring using national cancer registries, molecular tumour profiling and improved early detection and genetic testing initiatives. Understanding regional variances and risk factors for paediatric brain tumour patients can inform future studies, focused prevention campaigns, and improved survival and treatment outcomes. This information was gathered from reputable websites such as DOAJ (directory of open access journals), ERIC (education resources information centre), ScienceDirect, PubMed and google scholar. The diagram has taken from biorander while the graph, pie chart and flow chart are made in MS word.
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creator: Hasta Behra
creator: Adlin Asha V
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-04-03
publication date: 2026-04-03
starting page: 40
ending page: 49
doi: 10.48165/aabr.2026.3.1.04

Tinospora cordifolia GCMS profiling and cytotoxic effect on HCT 116- In vitro assay
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description: An assessment of Tinospora cordifolia extract’s (TCE) antimicrobial and antioxidant properties was undertaken in light of its possible application as cytotoxic against HCT116. Compounds from the stem were Soxhlet extracted with ethyl acetate and identified through GCMS. Antibacterial, antioxidant and HCT cytotoxicity of extract was studied by conventional standard methods. The GC–MS profile highlights a chemically diverse phytochemical composition, with both major and minor compounds potentially responsible for natural antimicrobial and antioxidant agent. The extract has broad spectrum antibacterial activity at concentration dependent manner against both Gram positive and negative clinical pathogens with relative inhibition 83 to 107%. Among the tested antioxidant assay the extract showed the strongest DPPH scavenging with an IC₅₀ value of 12.07 µg/mL, which, although higher than the standard ascorbic acid. Treatment of HCT116 colorectal carcinoma cells with TCE resulted in a dose-dependent reduction in cell viability. Nonlinear regression analysis of the MTT assay revealed an IC₅₀ value of 359 µg/ml, with viability decreasing from ~80% at 300 µg/ml to <10% at 900–1000 µg/ml. Morphological examination and apoptosis assays further confirmed that cell death was predominantly apoptotic nature of cancerous cells. The molecular docking of compounds 2-Fluoro-3-trifluoromethylbenzoic acid found to be strongest binding affinity and non-toxic drug likeness identified as promising new anticancer compound.
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creator: S Manimozhi
creator: V Sumathi
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-12-09
publication date: 2025-12-09
starting page: 6
ending page: 14
doi: 10.48165/aabr.2025.2.2.02

A Comprehensive Review Of Multi-Omics, Network Pharmacology, And Artificial Intelligence Approaches To Heart Failure
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description: Heart failure continues to be a pandemic of the twenty-first century, a major contributor to which are chronic diseases and the increasing number of elderly people. The transition from the outdated “dropsy” to the modern neurohormonal theory of the illness is reviewed. Beta-blockers, MRAs, ARNIs, and SGLT2 inhibitors are the core “scaffold” of medicines that have improved nearly all patient outcomes, which is why treatment has revolutionized itself. However, since genetics recognizes the genetic variability of heart failure situations, it holds the key to the sector’s future. The goal of this effort is to identify illness endotypes for customized therapeutic care, driven by bioinformatics and multi-omics data. On top of that, the scientists are keen on implementing the same technology and in silico approaches to explore phytocomplexes with multitarget activity. AI and machine learning have dramatically transformed the pharmaceutical industry, disease prediction, and diagnostic procedures. This paper elucidates the evolution of heart failure management from an indiscriminate, reactive model to a tailored, systems-based, preventive paradigm.
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creator: Fatima Patel
creator: Deepali KS
creator: Vaibhav Sabale
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-01-05
publication date: 2026-01-05
starting page: 13
ending page: 28
doi: 10.48165/aabr.2026.3.1.02

Unraveling Human Metapneumovirus: A Full-Spectrum Review Of Its History, Global Burden, Bioinformatics Advances, And Current Gaps
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description: Human metapneumovirus (HMPV) is one of the primary sources of severe respiratory infections worldwide. The threat level of the virus is almost the same as that of influenza and RSV, and it is mostly difficult for the vulnerable trio of neonates, the elderly, and immunocompromised patients to deal with. Although it took approximately four decades from the time it had been circulating before it was identified in 2001, it still has no vaccine or antiviral drugs. The current review sheds light on HMPV’s genetic lineages and worldwide transmission, emphasizing how bioinformatics has changed its research. Advanced sequencing enables detailed phylogenetic tracking of the virus, whereas computational tools, such as AlphaFold2, help obtain an accurate protein structure. Such breakthroughs can attract the development of drugs through molecular docking and epitope generation for vaccine design. The molecular dynamics simulations also show the viral fusion protein conformational transitions, among other key processes, On the road to success there are still some major gaps in knowledge, such as host receptor identification Integrating these computational approaches is essential to accelerate the development of therapies and reduce the global HMPV burden.
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creator: Deepali KS
creator: Fatima Patel
creator: Vaibhav Sabale
rights: Copyright (c) 2026 Advances in Applied Biological Research
date: 2026-01-05
publication date: 2026-01-05
starting page: 1
ending page: 12
doi: 10.48165/aabr.2026.3.1.01

The Heritage on Our Plates: Reviving Traditional Diets for Modern Wellbeing
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description: Traditional dietary patterns, developed over centuries, offer balanced nutrient profiles, cultural sustainability, and health benefits that are increasingly relevant in addressing modern diet-related chronic diseases. With rising rates of non communicable diseases (NCDs) such as cardiovascular disease, type 2 diabetes and obesity, global interest in diets like the Mediterranean, Indian traditional, Japanese and Nordic patterns has surged. These diets are rich in whole grains, fresh vegetables, fruits, legumes, nuts, healthy fats and fermented foods and low in processed sugars and trans fats. This review synthesizes recent literature (2018–2025) on the nutrient composition, health outcomes and potential integration strategies of traditional diets in contemporary health systems. Also explore the challenges of preserving cultural dietary practices in an era dominated by fast food and ultra-processed products. Data indicate that adopting traditional diets can reduce cardiovascular risk by up to 30%, improve glycaemic control, and support gut microbiota diversity, leading to improved overall well-being. The review concludes with recommendations for policymakers, healthcare providers, and individuals to adapt and sustain these dietary patterns in the modern context.
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creator: Prerna Shekhawat
creator: Sarla Lakhawat
creator: Harshita Bordia
creator: Khyati Joshi
creator: Alok Kumar Saini
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-08-27
publication date: 2025-08-27
starting page: 1
ending page: 5
doi: 10.48165/aabr.2025.2.2.01

Deep Vein Thrombosis associated with Cesarean Delivery: An Overview Illustrative Study
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description: The risk of deep vein thrombosis (DVT) in women is strongly associated with pregnancy, the risk increasing by 5 to 10 times. This risk then gradually increases until it peaks during and after delivery. Blood clots are one of the most feared complications after childbirth. They usually occur in the legs or pelvis and can dislodge and travel to the lungs, causing pulmonary embolism. It can be controlled on this state by using blood-thinning medications to avoid death. This problem occurs as one complication of a cesarean section, which involves a surgical technique for delivering a baby through an incision in the abdomen and uterus. It is performed as an alternative to vaginal delivery. Although the risk of venous thromboembolism increases with surgical delivery, there is no consensus on the prevention of clots after cesarean section.
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creator: Maryam Abd Al Kareem
creator: Ali Fadhil Obaid
creator: Hayder M Obaid
creator: Zainab Abdulameer Abdulrasol
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-08-06
publication date: 2025-08-06
starting page: 12
ending page: 16
doi: 10.48165/aabr.2025.2.1.03

Risk for Diabetic Foot Ulcer Associated with Type 2 Diabetes Mellitus Patients
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description: Background: One of the most frequent side effects of individuals with poorly managed type 2 diabetes is ulcers in their feet caused by diabetes. It is typically brought about by inadequate care for the feet, blood vessel disease with intrinsic nerve damage, or low blood sugar levels. It additionally serves as one of the leading causes of limb loss and bone disease within the leg. Objective: to assess Risk for Diabetic Foot Ulcer Associated with Type 2 Diabetes Mellitus Patients. Materials and Procedures: A descriptive study conducted at Al-Hilla Teaching Hospital to assess Risk for Diabetic Foot among Patients With Type 2 Diabetes Mellitus. Data collection take place from December 15, 2023, to February 30, 2024. The questionnaire’s validity was ensured through expert review Results: The high percentage %62 (50-60) years of age between (20-30) years, regarding the sex the result recorded 26(52.0) were female ,11(22.0) was post graduate regarding educational status, the result recorded 43(86.0) were married, related to occupation the result recorded 37 (74.0) were unemployed, and 13(26.0) were unemployed, related to residency the result recorded 31(62.0) were urban resident. Conclusions: highlights the significance of the study’s findings regarding diabetes foot risk among female, with old age play significant function in the progression of type two diabetic foot ulcers patient.
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creator: Wefaqq Mahdi Hadi
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-08-01
publication date: 2025-08-01
starting page: 33
ending page: 40
doi: 10.48165/aabr.2024.1.2.05

Role of Vitamin C in Health and Disease: A Comprehensive Review
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description: Vitamin C (ascorbic acid) is a water-soluble vitamin with vital roles in human health. It functions as a potent antioxidant, supports the immune system, aids in collagen synthesis, and enhances iron absorption. The deficiency of vitamin C leads to scurvy, while its adequate intake is associated with numerous health benefits, including reduced risk of chronic diseases such as cardiovascular disease, cancer, and neurodegenerative disorders. Supplementation with vitamin C appears to be able to both prevent and treat respiratory and systemic infections. This review provides an analysis of the role of vitamin C in health and disease, its dietary sources, recommended intake, and its therapeutic applications based on recent literature.
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creator: Harshita Bordia
creator: Sarla Lakhawat
creator: Prerna Shekhawat
creator: Khyati Joshi
creator: Alok Kumar Saini
rights: Copyright (c) 2025 Advances in Applied Biological Research
date: 2025-07-16
publication date: 2025-07-16
starting page: 1
ending page: 5
doi: 10.48165/aabr.2025.2.1.01

Role of DIP Diet in Managing Blood Transfusion-Dependent Thalassemia Major: A Case Study of Integrative Therapies”
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description: Thalassemia Major, a severe genetic blood disorder, necessitates frequent blood transfusions to manage low hemoglobin levels. This case highlights the recovery journey of Dibyanshu Pani, a 4-year-old boy from Odisha, diagnosed with Blood Transfusion Dependent Thalassemia Major in April 2023. Initially treated at SCB Medical College, Cuttack, and subsequently in Mumbai, Dibyanshu underwent frequent transfusions every 20 days to maintain his hemoglobin levels, which fluctuated between 5 and 9. In July 2023, his family opted for an alternative approach under Dr. Namita’s guidance, incorporating integrative therapies such as the DIP Diet, Living Water Therapy, Sunlight Exposure, and HWI Therapy. Remarkably, Dibyanshu’s condition stabilized, reducing his dependence on transfusions. By October 2023, his hemoglobin levels were maintained between 6.8 and 7.5 without regular transfusions. His family’s adherence to integrative therapies transformed his prognosis, with the frequency of transfusions decreasing to once every eight months. In August 2024, a sudden episode of diarrhea necessitated a single transfusion. Today, Dibyanshu leads a healthy life, free from medications, following a holistic lifestyle. This case underscores the potential of integrative therapies in managing chronic conditions like Thalassemia Major, reducing medical dependence, and improving quality of life.
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creator: Biswaroop Roy Chowdhury
rights: Copyright (c) 2024 Advances in Applied Biological Research
date: 2025-01-24
publication date: 2025-01-24
starting page: 27
ending page: 32
doi: 10.48165/aabr.2024.1.2.04

Evaluating the Efficacy of Ayurvedic Treatments in Stage V Chronic Kidney Disease: A Case Report
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description: Chronic Kidney Disease, Ayurveda, Mutraaghaata symptoms significantly improved. The patient’s key laboratory parameters, such as serum creatinine, urea, and serum uric acid, also showed marked improvement, trending toward normal levels at the time of discharge. The treatment regimen included Ayurvedic oral medications like Tab. Asthipurak, Tab. Chander Vati, Renal Support syrup, and GFR powder, complemented by Panchakarma procedures such as Awgaha Swedan, Matra Basti, Kashaya Basti, and Shiroabhyanga. The results of this case indicate that Ayurvedic interventions can lead to significant improvements in both biochemical markers and clinical symptoms in patients with Stage V CKD. These findings suggest that Ayurveda may offer a promising complementary or alternative approach to conventional CKD treatment, highlighting the need for further research in this area
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creator: Manish Acharya Ji
creator: Gitika Chaudhary
creator: Richa
creator: Suyash Pratap Singh
creator: Manjeet Singh
rights: Copyright (c) 2024
date: 2024-12-19
publication date: 2024-12-19
starting page: 21
ending page: 26
doi: 10.48165/aabr.2024.1.2.03

Exploring the Versatility of Bacillus spp. Secondary Metabolites: its mode of action and application in various field
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description: Bacillus spp. is a rich source of various Secondary Metabolites (SMs) that are used for diverse purposes. These include lipopeptides, non-ribosomal peptides, polyketides and many more which possess strong antimicrobial, antifungal and insecticidal properties thereby making them useful ingredients for biotechnology, agriculture, cosmetics, healthcare and food preservation. This review provides an overview on the current understanding of Bacillus SM’s diversity that has been overlooked to some extent as well as their mode-of-action and application prospects. Recent technological advancements—such as metagenomics, synthetic biology, CRISPR-Cas9, machine learning, microfluidics, and high-throughput screening—have accelerated discoveries and optimized SM production. The use of SMs as plant growth promoting compound in agriculture controlling pathogens while may also have pharmaceutical, nutraceutical and cosmetic applications. Furthermore, they possess a broad range of industrial applications, including use in detergents and food preservatives, offering more versatility and environmental friendliness compared to chemical alternatives. Though there has been significant progress there still exist major knowledge gaps in regulation and ecological roles played by SMs that need to be addressed through research. As we uncover the secrets behind the production and various application of SMs, microorganisms can become effective allies in addressing global challenges for a healthier, more sustainable planet.
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creator: Krunal kumar Dholiya
creator: Nilesh Kumar Pandya
rights: Copyright (c) 2024 Advances in Applied Biological Research
date: 2024-12-05
publication date: 2024-12-05
starting page: 9
ending page: 20
doi: 10.48165/aabr.2024.2.2

Ethnomedicinal Plant Treatment Practices in Vouge for Curing Different Ailments in the Villages of Alluru Sitarama Raju District, the Eastern Ghats of Andhra Pradesh, India
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description: This paper deals with the Ethno medicinal treatment practices for treating different types of ailments. The present survey comprises of totally fifty Ethno-medicinal formulae which provides information in detail on the therapeutic values of 34 plant species belonging to 31 genera and 24 families, covering 21 different ailments or health exigencies. Information on botanical names, vernacular names, families, plant parts & used methods of preparation of drugs as well administration are presented in a detailed manner. The Information collected in this study would act as vital data for scientific community.
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creator: N V Jayanth Devakoti Babu
creator: D S Madhava Rao
creator: G M Narasimha Rao
rights: Copyright (c) 2024 Advances in Applied Biological Research
date: 2024-10-14
publication date: 2024-10-14
starting page: 1
ending page: 8
doi: 10.48165/aabr.2024.1.2.01

Molecular Identification of Family Colubridae from Punjab, Pakistan
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description: The present one year study was extended from May 2019 to March 2020 was conducted in selected sites of Punjab. This study focuses on the molecular identification and morphometric analysis of two snake species, Platyceps rhodorachis (Cliff Racer) and Amphiesma stolatum (Buff Striped Keelback) collected from selected sites in Punjab, Pakistan. Each captured specimen was tagged with specific number and identified using morphological keys. Total genomic DNA was extracted from preserved tissues and amplified using COI primers set. After trimming ambiguous bases, the obtained COI fragments of Platyceps rhodorachis was 668 bp while fragments of Amphiesma stolatum was 639 bp. The COI fragments aligned with available sequence from NCBI comprised of 620 bp. The DNA sequences have shown reliable and exact species identification. The mean intraspecific identities of Platyceps rhodorachis (Cliff Racer) and Amphiesma stolatum (buff striped keelback) was 0.11±0.01 and respectively based of p-distance. Different molecular markers have been used in this study. Platyceps rhodorachis and Amphiesma Solatum successfully amplified using COI gene. It can be concluded that, identification of reptiles on morphological basis is still considered authentic. However, large scale molecular analysis of these taxa is required for exact species identification and to report any new species from area.
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creator: Sadia Ali
creator: Sehresh Ghafoor
creator: Umair Ahmad
creator: Areej Fatima
creator: Saba Hanif
creator: Hamad Alam
creator: Muhammad Imran
creator: Aliza Umar
creator: Iqra Ehsan
creator: laiba Nawaz
creator: Waqas Ali
rights: Copyright (c) 2024 Advances in Applied Biological Research
date: 2024-10-14
publication date: 2024-10-14
starting page: 14
ending page: 21
doi: 10.48165/aabr.2024.1.3

Isolation and Identification of Bacteria from the Oral Cavity of Monitor Lizard (Varanus bengalensis)
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description: The current research was carried out in the Kasur district, Punjab, Pakistan with the duration of July 2021 to June 2022. The purpose of study was to isolate and identify the bacterial community in the oral cavity of monitor lizard (Varanus bengalensis). As monitor lizards are ectotherm reptiles so they spent most of their winter season from November to March in hibernation. So, sampling is done before and after the hibernation period. Ten specimens were captured from the study area by the direct encounter and also using hand nets and pitfall traps. The collected samples were transferred to the University of Veterinary Animal Sciences, Ravi Campus, Pattoki at the Postgraduate Lab, Department of Wildlife and Ecology. Specimens were handled with care to aviod injury. The cotton-tipped swab stick was used to collect a saliva sample from the oral cavity by using a sterile mouth gag. At least three cotton swab samples were taken from each specimen.Each swab sample was stored in sterile buffered peptone water in falcon tubes at -4º C. The solution from the tubes was streaked over Nutrient agar (NA), Mannitol Salt (MS) agar, Xylose Lysine Deoxycholate (XLD) agar and Trypticase Soya agar with 5% Sheep Blood agar. All of the plates were cultured at 36±°C in an incubator for 24–48 hours. Gram staining was used to identify descriptive colony morphology. Isolates were identified primarily based on colony morphology on selective media, Gram nature, motility test, and pigment production. For possible identification, the selected colonies were sub-cultured on nutrient agar and Trypticase Soya agar (TSA). After that, isolated biochemical tests were carried out in order to identify them. Three most abundant bacterial species were investigated in present study including Salmonela typhi, Staphylococcus aureus and Pseudomonas aeruginosa their relative abundance would be statisticaly analyzed. Accordingly Salmonela typhi contained 43.33%, Staphylococcus aureus contained 46.67% and Pseud…
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creator: Adeel Anjum
creator: Ariba Masood
creator: Umme Ammar
creator: Sadia Arshid
creator: Rana Fazail Ahmed
creator: Aliza Umar
creator: Muhammad Imran
creator: Mudasar Hussain
creator: Moshin Masood
creator: Waqas Ali
rights: Copyright (c) 2024 Advances in Applied Biological Research
date: 2024-09-17
publication date: 2024-09-17
starting page: 32
ending page: 39
doi: 10.48165/aabr.2024.1.05